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Macitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.03 mL | 85.14 mL | 170.28 mL |
| 0.5 mM | 3.41 mL | 17.03 mL | 34.06 mL |
| 1 mM | 1.7 mL | 8.51 mL | 17.03 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.41 mL |
*The above data is based on the productmolecular weight 587.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21845 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 587.28 |
| Formula | C20H21Br2N5O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 556797-16-1 |
| SMILES | BrC1=CN=C(OCCOC2=C(C3=CC=C(Br)C=C3)C(NS(CCCC)(=O)=O)=NC=N2)N=C1 |
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