Macitentan

目录号: A11492

Endothelin receptor antagonist

Macitentan

Macitentan Chemical Structure

CAS NO. 441798-33-0

Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

库存: 现货

规格 价格 数量
5 mg
¥ 1,400.00
10 mg
¥ 2,700.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
Targets
ET-A ET-B
0.5 nM391 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17 mL 84.99 mL 169.99 mL
0.5 mM 3.4 mL 17 mL 34 mL
1 mM 1.7 mL 8.5 mL 17 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 588.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11492
MECHANISM OF ACTION Antagonist
M. Wt 588.27
Formula C19H20Br2N6O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 441798-33-0
Synonyms ACT 064992, ACT-064992, ACT064992
SMILES CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br

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