Macitentan
目录号: A11492
Endothelin receptor 拮抗剂
Macitentan 是一种口服活性的非肽类双重内皮素 ETA 和 ETB 受体拮抗剂，用于潜在治疗特发性肺纤维化（IPF）和肺动脉高压（PAH）。
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生物活性
| Discription | Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH). | |||||
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| Cell Research |
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产品信息
| 目录号 | A11492 |
|---|---|
| 分子式 | C19H20Br2N6O4S |
| 分子量 | 588.27 |
| CAS号 | 441798-33-0 |
| SMILES | CCCNS(=O)(=O)NC1=C(C(=NC=N1)OCCOC2=NC=C(C=N2)Br)C3=CC=C(C=C3)Br |
| 其他名称 | ACT 064992, ACT-064992, ACT064992 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 87 mg/mL (147.88 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17 mL | 84.99 mL | 169.99 mL |
| 0.5 mM | 3.4 mL | 17 mL | 34 mL |
| 1 mM | 1.7 mL | 8.5 mL | 17 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.4 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 441798-33-0 | 441798-33-0 供应商 | 441798-33-0 花费 | 441798-33-0 生产商 | 订购 441798-33-0 | 441798-33-0 代理商