Mapatumumab (HGS-ETR1) is a fully human IgG1 monoclonal antibody designed as an agonist for tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). This antibody selectively binds to TRAIL-R1, potentially inducing apoptosis in cells expressing this receptor. Mapatumumab is primarily utilized in oncological research to study its efficacy and mechanism in promoting cancer cell apoptosis.
Mapatumumab (HGS-ETR1) is a fully human IgG1 monoclonal antibody designed as an agonist for tumor necrosis factor-related apoptosis-inducing ligand receptor 1 (TRAIL-R1). This antibody selectively binds to TRAIL-R1, potentially inducing apoptosis in cells expressing this receptor. Mapatumumab is primarily utilized in oncological research to study its efficacy and mechanism in promoting cancer cell apoptosis.
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