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Marimastat

促销

MMP 抑制剂

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产品目录号: A12826

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Marimastat 5mg A12826-5
¥ 650.00
Marimastat 10mg A12826-10
¥ 1,100.00
Marimastat 25mg A12826-25
¥ 2,100.00
Marimastat 50mg A12826-50
¥ 3,300.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Marimastat acted as a broad-spectrum matrix metalloproteinase inhibitor.

Marimastat

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Marimastat 发表的文献 (2)
  • Lv Y, .et al. Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells, ACS Nano, 2018, Feb 27;12(2):1519-1536 PMID: 29350904
  • ChaoQin, .et al. Matrix metalloproteinases sensitive multifunctional micelles for inhibition of metastatic tumor growth and metastasis, Powder Technol, 2018, In Press

Chemical Information

目录号 A12826
Mechanism of action Inhibitor
分子量 331.41
化学分子式 C15H29N3O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 154039-60-8
Synonyms N/A
SMILES code CC(C)C[C@H]([C@@H](C(=O)NO)O)C(=O)N[C@H](C(=O)NC)C(C)(C)C
化学名称 (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(m?ethylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-me?thylpropyl)butanediamide

生物活性

Description
Marimastat acted as a broad-spectrum matrix metalloproteinase inhibitor.
Targets
Target Value
MMP-9IC50: 3nM
MMP-1IC50: 5nM
MMP-2IC50: 6nM
MMP-14IC50: 9nM
MMP-7IC50: 16nM
MMP-3IC50: 230nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.17 mL 150.87 mL 301.74mL
0.5 mM 6.03 mL 30.17 mL 60.35 mL
1 mM 3.02 mL 15.09 mL 30.17 mL
5 mM 0.6 mL 3.02 mL 6.03 mL

*The above data is based on the productmolecular weight 331.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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