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Masitinib mesylate

KIT/PDGFR 抑制剂

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产品目录号: A15152

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Masitinib mesylate 50mg A15152-50
¥ 1,100.00
Masitinib mesylate 200mg A15152-200
¥ 2,500.00
Masitinib mesylate 500mg A15152-500
¥ 4,700.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Masitinib mesylate is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms.

Masitinib mesylate

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Chemical Information

目录号 A15152
Mechanism of action Inhibitor
分子量 594.75
化学分子式 C29H34N6O4S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1048007-93-7
Synonyms AB1010 mesylate, Masivet mesylate, AB-1010 mesylate, AB 1010 mesylate
SMILES code CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5.CS(=O)(=O)O
化学名称 methanesulfonic acid;4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-yl-1,3-thiazol-2-yl)amino]phenyl]benzamide

生物活性

Description
Masitinib mesylate is a novel inhibitor for Kit and PDGFRα/β with IC50 of 200 nM and 540 nM/800 nM, weak inhibition to ABL and c-Fms.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.81 mL 84.07 mL 168.14mL
0.5 mM 3.36 mL 16.81 mL 33.63 mL
1 mM 1.68 mL 8.41 mL 16.81 mL
5 mM 0.34 mL 1.68 mL 3.36 mL

*The above data is based on the productmolecular weight 594.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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