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Masitinib ( AB1010)


c-Kit 抑制剂

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产品目录号: A10558


产品名 目录号 价格 数量
Masitinib 10mg A10558-10
¥ 500.00
Masitinib 25mg A10558-25
¥ 900.00
Masitinib 50mg A10558-50
¥ 1,100.00
Masitinib 100mg A10558-100
¥ 1,680.00
Masitinib ( AB1010) 10mM * 1mL in DMSO A10558-10mM-D
¥ 500.00



Masitinib (AB1010) is a protein tyrosine kinase inhibitor.

Masitinib ( 	AB1010)




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Chemical Information

目录号 A10558
Mechanism of action Inhibitor
分子量 498.6
化学分子式 C28H30N6OS
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 790299-79-5
Synonyms AB1010, Masivet
化学名称 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide


Masitinib (AB1010) is a protein tyrosine kinase inhibitor.
Target Value
KitIC50: 200nM
LynBIC50: 510nM
PDGFRαIC50: 540nM
PDGFRβIC50: 800nM
Abl1IC50: 1.20μM
c-FmsIC50: 1.48μM
SrcIC50: 1.87μM
HckIC50: 2.0μM
FLT3IC50: >10μM
VEGFR1IC50: >10μM
VEGFR2IC50: >10μM
EGFRIC50: >10μM
FGFR1IC50: >10μM
FGFR3IC50: >10μM
IGF-1RIC50: >10μM
c-MetIC50: >10μM
c-RetIC50: >10μM
JAK2IC50: >10μM
BTKIC50: >10μM
BmxIC50: >10μM
SykIC50: >10μM
FesIC50: >10μM
PKCαIC50: >10μM
Pim1IC50: >10μM
Akt1IC50: >10μM


Solubility (25°C) * In vitro DMSO 100 mg/mL (200.54 mM)
Water <1 mg/mL (<1 mM)
Ethanol 4 mg/mL (8.02 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.06 mL 100.28 mL 200.56mL
0.5 mM 4.01 mL 20.06 mL 40.11 mL
1 mM 2.01 mL 10.03 mL 20.06 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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