Masitinib ( AB1010) Chemical Structure

CAS NO. 790299-79-5

Masitinib (AB1010) is a protein tyrosine kinase inhibitor.

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 900.00
50 mg
¥ 980.00
100 mg
¥ 1,680.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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Masitinib (AB1010) is a protein tyrosine kinase inhibitor.
Targets
Target Value
KitIC50: 200nM
LynBIC50: 510nM
PDGFRαIC50: 540nM
PDGFRβIC50: 800nM
Abl1IC50: 1.20μM
c-FmsIC50: 1.48μM
SrcIC50: 1.87μM
HckIC50: 2.0μM
FLT3IC50: >10μM
VEGFR1IC50: >10μM
VEGFR2IC50: >10μM
EGFRIC50: >10μM
FGFR1IC50: >10μM
FGFR3IC50: >10μM
IGF-1RIC50: >10μM
c-MetIC50: >10μM
c-RetIC50: >10μM
JAK2IC50: >10μM
BTKIC50: >10μM
BmxIC50: >10μM
SykIC50: >10μM
FesIC50: >10μM
PKCαIC50: >10μM
Pim1IC50: >10μM
Akt1IC50: >10μM
In vitro (25°C) DMSO 100 mg/mL (200.54 mM)
Water <1 mg/mL (<1 mM)
Ethanol 4 mg/mL (8.02 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.06 mL 100.28 mL 200.56 mL
0.5 mM 4.01 mL 20.06 mL 40.11 mL
1 mM 2.01 mL 10.03 mL 20.06 mL
5 mM 0.4 mL 2.01 mL 4.01 mL

*The above data is based on the productmolecular weight 498.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10558
MECHANISM OF ACTION Inhibitor
M. Wt 498.6
Formula C28H30N6OS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 790299-79-5
Synonyms AB1010, Masivet
SMILES CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5

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