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Mavoglurant is a structurally novel, non-competitive mGlu5 receptor antagonist, has an IC50 of 30 nM in a functional assay with human mGluR5.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.91 mL | 159.55 mL | 319.09 mL |
| 0.5 mM | 6.38 mL | 31.91 mL | 63.82 mL |
| 1 mM | 3.19 mL | 15.95 mL | 31.91 mL |
| 5 mM | 0.64 mL | 3.19 mL | 6.38 mL |
*The above data is based on the productmolecular weight 313.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21223 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 313.39 |
| Formula | C19H23NO3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 543906-09-8 |
| Synonyms | AFQ056, AFQ 056, AFQ-056 |
| SMILES | CC1=CC(C#C[C@]2(O)CCC[C@]3([H])[C@@]2([H])CCN3C(OC)=O)=CC=C1 |
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