Mazorelvimab (CTB012) is a humanized IgG1?? monoclonal antibody designed to target the rabies virus (RABV) by binding to non-overlapping epitopes on the RABV glycoprotein. This antibody specifically interacts with highly discontinuous, conserved residues that are distinct from antigenic site III, ensuring unique specificity. Mazorelvimab is primarily investigated for its potential use in the prevention of rabies, offering a promising therapeutic approach in rabies prophylaxis.
Mazorelvimab (CTB012) is a humanized IgG1?? monoclonal antibody designed to target the rabies virus (RABV) by binding to non-overlapping epitopes on the RABV glycoprotein. This antibody specifically interacts with highly discontinuous, conserved residues that are distinct from antigenic site III, ensuring unique specificity. Mazorelvimab is primarily investigated for its potential use in the prevention of rabies, offering a promising therapeutic approach in rabies prophylaxis.
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