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MC-Val-Cit-PAB

MC-Val-Cit-PAB

Name: MC-Val-Cit-PAB
SKU: A20571

目录号: A20571

MC-Val-Cit-PAB Chemical Structure

CAS NO. 159857-80-4

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.

库存：现货

规格	价格	数量
100 mg	￥ 5,400.00
500 mg	￥ 16,200.00

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生物活性

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.

溶解度 *

In vitro	DMSO	98 mg/mL (171.13 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.46 mL	87.31 mL	174.63 mL
0.5 mM	3.49 mL	17.46 mL	34.93 mL
1 mM	1.75 mL	8.73 mL	17.46 mL
5 mM	0.35 mL	1.75 mL	3.49 mL

*The above data is based on the productmolecular weight 572.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20571
M. Wt	572.65
Formula	C28H40N6O7
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	159857-80-4
SMILES	CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)NC(CCCCCN2C(C=CC2=O)=O)=O