MC180295
目录号: A18892
CDK9 抑制剂
MC180295 是一种高度选择性的 CDK9 抑制剂(IC50 = 5 nM)。MC180295 也能抑制 GSK-3α 和 GSK-3β。MC180295 ((rel)-MC180295) 具有强大的抗肿瘤效果。
Discription | MC180295 is a highly selective CDK9 inhibitor (IC50 = 5 nM). MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect. | ||
---|---|---|---|
Targets |
|
目录号 | A18892 |
---|---|
分子式 | C17H18N4O3S |
分子量 | 358.41 |
CAS号 | 2237942-08-2 |
SMILES | O=C(C1=C(N)N=C(N[C@@H]2C(C3)CCC3C2)S1)C4=CC=CC=C4[N+]([O-])=O |
其他名称 | MC180295; MC-180295; MC 180295; |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 64 mg/mL (178.56 mM) | |
Water | 64 mg/mL (178.56 mM) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.9 mL | 139.51 mL | 279.01 mL |
0.5 mM | 5.58 mL | 27.9 mL | 55.8 mL |
1 mM | 2.79 mL | 13.95 mL | 27.9 mL |
5 mM | 0.56 mL | 2.79 mL | 5.58 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2