Mepolizumab (SB 240563) is a humanized monoclonal antibody designed to specifically bind to and neutralize interleukin-5 (IL-5). IL-5 is a critical cytokine that regulates eosinophil proliferation, activation, and survival. This antibody is utilized in research focused on eosinophilic conditions, including eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma, providing a valuable tool for investigating the pathophysiology and potential therapeutic interventions for these diseases.
Mepolizumab (SB 240563) is a humanized monoclonal antibody designed to specifically bind to and neutralize interleukin-5 (IL-5). IL-5 is a critical cytokine that regulates eosinophil proliferation, activation, and survival. This antibody is utilized in research focused on eosinophilic conditions, including eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic asthma, providing a valuable tool for investigating the pathophysiology and potential therapeutic interventions for these diseases.
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