Merafloxacin

目录号: A22483

Merafloxacin

Merafloxacin Chemical Structure

CAS NO. 91188-00-0

Merafloxacin, also known as CI 934, is a fluoroquinolone antibacterial, which was also identified as a ?1 PRF inhibitor of SARS-CoV-2. Frameshift inhibition by merafloxacin is robust to mutations within the pseudoknot region and is similarly effective on ?1 PRF of other beta coronaviruses. Importantly, frameshift inhibition by merafloxacin substantially impedes SARS-CoV-2 replication in Vero E6 cells, thereby providing the proof of principle of targeting ?1 PRF as an effective antiviral strategy for SARS-CoV-2.

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,500.00
50 mg
¥ 7,200.00
100 mg
¥ 13,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Merafloxacin, also known as CI 934, is a fluoroquinolone antibacterial, which was also identified as a ?1 PRF inhibitor of SARS-CoV-2. Frameshift inhibition by merafloxacin is robust to mutations within the pseudoknot region and is similarly effective on ?1 PRF of other beta coronaviruses. Importantly, frameshift inhibition by merafloxacin substantially impedes SARS-CoV-2 replication in Vero E6 cells, thereby providing the proof of principle of targeting ?1 PRF as an effective antiviral strategy for SARS-CoV-2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.36 mL 131.78 mL 263.57 mL
0.5 mM 5.27 mL 26.36 mL 52.71 mL
1 mM 2.64 mL 13.18 mL 26.36 mL
5 mM 0.53 mL 2.64 mL 5.27 mL

*The above data is based on the productmolecular weight 379.4078. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A22483
M. Wt 379.4078
Formula C19H23F2N3O
Solubility DMSO
Purity >98%
Storage at -20°C 2 years
CAS No. 91188-00-0
Synonyms CI 934, CI-934, CI934, Merafloxacin,
SMILES O=C(C1=CN(CC)C2=C(C=C(F)C(N3CC(CNCC)CC3)=C2F)C1=O)O

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