Methotrexate (Abitrexate)

Name: Methotrexate (Abitrexate)
SKU: A10021
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A10021

DHFR 抑制剂

美托洛塞是一种细胞毒性药物，它抑制胸苷酸合成酶和新生嘌呤合成。

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Grouped product items
规格	价格	库存
50mg	¥210.00	现货
100mg	¥315.00	现货
200mg	¥490.00	现货
500mg	¥875.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

Methotrexate is a cytotoxic agent that inhibits thymidylate synthetase and de novo purine synthesis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10021
分子式	C20H22N8O5
分子量	454.44
CAS号	CAS: 59-05-2
SMILES	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
其他名称	MTX, amethopterin, Rheumatrex, Trexall
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 89 mg/mL (195.84 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.01 mL	110.03 mL	220.05 mL
0.5 mM	4.4 mL	22.01 mL	44.01 mL
1 mM	2.2 mL	11 mL	22.01 mL
5 mM	0.44 mL	2.2 mL	4.4 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂