Methotrexate (Abitrexate)

目录号: A10021

DHFR inhibitor

Methotrexate (Abitrexate)

Methotrexate (Abitrexate) Chemical Structure

CAS NO. CAS: 59-05-2

Methotrexate is a cytotoxic agent that inhibits thymidylate synthetase and de novo purine synthesis.

库存: 现货

规格 价格 数量
100 mg
¥ 500.00
200 mg
¥ 750.00
500 mg
¥ 1,300.00
10mM * 1mL in DMSO
¥ 610.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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Methotrexate is a cytotoxic agent that inhibits thymidylate synthetase and de novo purine synthesis.
In vitro (25°C) DMSO 90 mg/mL (198.04 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.01 mL 110.03 mL 220.05 mL
0.5 mM 4.4 mL 22.01 mL 44.01 mL
1 mM 2.2 mL 11 mL 22.01 mL
5 mM 0.44 mL 2.2 mL 4.4 mL

*The above data is based on the productmolecular weight 454.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10021
MECHANISM OF ACTION Inhibitor
M. Wt 454.44
Formula C20H22N8O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. CAS: 59-05-2
Synonyms MTX, amethopterin, Abitrexate, Rheumatrex, Trexall
SMILES CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

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