MF-438
目录号: A20963
SCD1 抑制剂
MF-438 是一种效力强大且可口服生物利用的硬脂酰辅酶A去饱和酶1（SCD1）抑制剂，其对 rSCD1 的 EC50 为 2.3 nM。
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生物活性
| Discription | MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1. | |||||
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| Cell Research |
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产品信息
| 目录号 | A20963 |
|---|---|
| 分子式 | C19H18F3N5OS |
| 分子量 | 421.44 |
| CAS号 | 921605-87-0 |
| SMILES | FC(C1=CC=CC=C1OC2CCN(C3=NN=C(C4=NN=C(C)S4)C=C3)CC2)(F)F |
| 其他名称 | MF438, MF 438 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 28 mg/mL (66.43 mM) | |
| Water | <1 mg/mL | ||
| Ethanol | 8 mg/mL (18.98 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.73 mL | 118.64 mL | 237.28 mL |
| 0.5 mM | 4.75 mL | 23.73 mL | 47.46 mL |
| 1 mM | 2.37 mL | 11.86 mL | 23.73 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.75 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 921605-87-0 | 921605-87-0 供应商 | 921605-87-0 花费 | 921605-87-0 生产商 | 订购 921605-87-0 | 921605-87-0 代理商