MG-132

目录号: A11043

Proteasome inhibitor

MG-132

MG-132 Chemical Structure

CAS NO. 133407-82-6

MG-132 is a potent cell-permeable inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 μM).

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 1,200.00
50 mg
¥ 2,000.00
100 mg
¥ 3,200.00
10mM * 1mL in DMSO
¥ 650.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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MG-132 is a potent cell-permeable inhibitor of proteasome (IC50 = 100 nM) and calpain (IC50 = 1.2 μM).
Targets
Proteasome (Cell-free assay)
100 nM
In vitro (25°C) DMSO 95 mg/mL (199.73 mM)
Water <1 mg/mL (<1 mM)
Ethanol 95 mg/mL (199.73 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80, pH 4 6 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.03 mL 105.13 mL 210.26 mL
0.5 mM 4.21 mL 21.03 mL 42.05 mL
1 mM 2.1 mL 10.51 mL 21.03 mL
5 mM 0.42 mL 2.1 mL 4.21 mL

*The above data is based on the productmolecular weight 475.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11043
MECHANISM OF ACTION Inhibitor
M. Wt 475.6
Formula C26H41N3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 133407-82-6
Synonyms Z-Leu-Leu-Leu-CHO, Z-LLL-CHO, MG132
SMILES CC(C)C[C@@H](C=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1

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