MGCD0103 (Mocetinostat)

目录号: A10586

HDAC 抑制剂

MGCD0103 (Mocetinostat)

MGCD0103 (Mocetinostat) Chemical Structure

CAS NO. 726169-73-9

MGCD0103 (Mocetinostat)是一种苯甲酰胺组蛋白脱乙酰基酶抑制剂,主要抑制组蛋白脱乙酰基酶1(HDAC1),但也抑制HDAC2,HDAC3和HDAC11。

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 500.00
25 mg
¥ 700.00
50 mg
¥ 990.00
10mM * 1mL in DMSO
¥ 550.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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MGCD0103 (Mocetinostat)是一种苯甲酰胺组蛋白脱乙酰基酶抑制剂,主要抑制组蛋白脱乙酰基酶1(HDAC1),但也抑制HDAC2,HDAC3和HDAC11。
Targets
Target Value
HDAC1IC50: 0.15μM
HDAC2IC50: 0.29μM
HDAC11IC50: 0.59μM
HDAC3IC50: 1.66μM
HDAC4IC50: >10μM
HDAC5IC50: >10μM
HDAC6IC50: >10μM
HDAC7IC50: >10μM
HDAC8IC50: >10μM
In vitro (25°C) DMSO 13 mg/mL (32.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.23 mL 126.14 mL 252.27 mL
0.5 mM 5.05 mL 25.23 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.23 mL
5 mM 0.5 mL 2.52 mL 5.05 mL

*The above data is based on the productmolecular weight 396.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10586
作用机制 Inhibitor (抑制剂)
M. Wt 396.4
Formula C23H20N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 726169-73-9
Synonyms MGCD-0103
SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4

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