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MGCD0103 (Mocetinostat)

目录号: A10586
HDAC 抑制剂
MGCD0103(Mocetinostat)是一种苯甲酰胺类组蛋白去乙酰化酶抑制剂,主要通过抑制组蛋白去乙酰化酶1(HDAC1),同时也能抑制HDAC2HDAC3HDAC11
Grouped product items
规格 价格 库存 数量
5mg
¥210.00
现货
10mg
¥315.00
现货
25mg
¥455.00
现货
50mg
¥630.00
现货
100mg
¥1,050.00
现货
200mg
¥1,400.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用MGCD0103 (Mocetinostat)发表的2篇文献
  • Mari Ishigami-Yuasa, .et al. , Biol Pharm Bull, 2019, 42, 448-452 PMID: 30828077
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
  • 生物活性
    Discription MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.
    Targets
    Target Value
    产品信息
    目录号 A10586
    分子式 C23H20N6O
    分子量 396.4
    CAS号 726169-73-9
    SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 12 mg/mL (30.27 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% Propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.23 mL 126.14 mL 252.27 mL
    0.5 mM 5.05 mL 25.23 mL 50.45 mL
    1 mM 2.52 mL 12.61 mL 25.23 mL
    5 mM 0.5 mL 2.52 mL 5.05 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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