MGL-3196

Name: MGL-3196
SKU: A13248

目录号: A13248

thyroid hormone receptor 激动剂

MGL-3196 Chemical Structure

CAS NO. 920509-32-6

MGL-3196是高度选择性的THR-β激动剂，EC50值为0.21 μM。旨在增加胆固醇向肝脏的吸收并增加其代谢。

库存：现货

规格	价格	数量
5 mg	￥ 1,100.00
10 mg	￥ 1,600.00
25 mg	￥ 2,800.00
50 mg	￥ 4,400.00

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生物活性

MGL-3196是高度选择性的THR-β激动剂，EC50值为0.21 μM。旨在增加胆固醇向肝脏的吸收并增加其代谢。

溶解度 *

In vitro	DMSO	80 mg/mL (183.81 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.98 mL	114.88 mL	229.77 mL
0.5 mM	4.6 mL	22.98 mL	45.95 mL
1 mM	2.3 mL	11.49 mL	22.98 mL
5 mM	0.46 mL	2.3 mL	4.6 mL

*The above data is based on the productmolecular weight 435.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13248
作用机制	Agonist (激动剂)
M. Wt	435.22
Formula	C17H12Cl2N6O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	920509-32-6
Synonyms	MGL3196, MGL 3196
SMILES	CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-n2nc(C#N)c(=O)[nH]c2=O)n[nH]c1=O