MGL-3196
目录号: A13248
thyroid hormone receptor 激动剂
MGL-3196 是一种口服小分子肝脏定向甲状腺激素受体激动剂,旨在增加胆固醇进入肝脏并增加其代谢。
| Discription | MGL-3196 is an orally small-molecule liver-directed thyroid hormone receptor agonist designed to increase cholesterol uptake into the liver and increase its metabolism. |
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| 目录号 | A13248 |
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| 分子式 | C17H12Cl2N6O4 |
| 分子量 | 435.22 |
| CAS号 | 920509-32-6 |
| SMILES | CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-n2nc(C#N)c(=O)[nH]c2=O)n[nH]c1=O |
| 其他名称 | MGL3196, MGL 3196 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 80 mg/mL (183.81 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.98 mL | 114.88 mL | 229.77 mL |
| 0.5 mM | 4.6 mL | 22.98 mL | 45.95 mL |
| 1 mM | 2.3 mL | 11.49 mL | 22.98 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2