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MI-1061

目录号: A18450
MDM2 抑制剂
MI-1061 是一种有效的、可口服生物利用度高、化学稳定性强的 MDM2 (MDM2-p53相互作用) 抑制剂(IC50=4.4 nM;Ki=0.16 nM)。MI-1061 强效激活 p53,诱导凋亡,并具有抗肿瘤活性。
Grouped product items
规格 价格 库存 数量
1mg
¥980.00
现货
5mg
¥2,415.00
现货
10mg
¥4,375.00
现货
25mg
¥8,400.00
现货
50mg
¥13,195.00
现货
100mg
¥20,895.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription MI-1061 is a potent, orally bioavailable, and chemically stable MDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM; Ki=0.16 nM). MI-1061 potently activates p53, induces apoptosis, and has anti-tumor activity.
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A18450
分子式 C30H26Cl2FN3O4
分子量 582.45
CAS号 1410737-34-6
SMILES O=C(O)C1=CC=C(NC([C@H](N2)[C@H](C3=CC=CC(Cl)=C3F)[C@]4(C(NC5=C4C=CC(Cl)=C5)=O)C62CCCCC6)=O)C=C1
其他名称 MI1061, MI 1061
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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