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MI-463

MI-463

Name: MI-463
SKU: A20755

目录号: A20755

menin-mLL interaction inhibitor

MI-463 Chemical Structure

CAS NO. 1628317-18-9

MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.

库存：现货

规格	价格	数量
1 mg	￥ 760.00
5 mg	￥ 2,270.00
10 mg	￥ 3,860.00
50 mg	￥ 11,590.00

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生物活性

MI-463 is a highly potent and orally bioavailable small molecule inhibitor of the menin-mLL interaction.

溶解度 *

In vitro	DMSO	84 mg/mL (173.36 mM)
	Water	Insoluble
	Ethanol	19 mg/mL (39.21 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.64 mL	103.19 mL	206.38 mL
0.5 mM	4.13 mL	20.64 mL	41.28 mL
1 mM	2.06 mL	10.32 mL	20.64 mL
5 mM	0.41 mL	2.06 mL	4.13 mL

*The above data is based on the productmolecular weight 484.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20755
M. Wt	484.54
Formula	C24H23F3N6S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1628317-18-9
Synonyms	MI 463; MI463
SMILES	FC(F)(F)CC(S1)=CC2=C1N=CN=C2NC3CCN(CC4=CC=C(NC(C#N)=C5)C5=C4C)CC3