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MI-773

MDM2 抑制剂

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产品目录号: A15440

库存状态:中国现货中国现货

产品名 目录号 价格 数量
MI-773 5mg A15440-5
¥ 1,000.00
MI-773 10mg A15440-10
¥ 1,800.00
MI-773 25mg A15440-25
¥ 4,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.

MI-773

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Chemical Information

目录号 A15440
Mechanism of action Inhibitor
分子量 562.5
化学分子式 C29H34Cl2FN3O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1303607-60-4
Synonyms SAR405838,MI 773, MI773
SMILES code CC(C)(C)CC1C2(C(C(N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O
化学名称 (2'S,3R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluorophenyl)-N-((1r,4R)-4-hydroxycyclohexyl)-2'-neopentyl-2-oxospiro[indoline-3,3'-pyrrolidine]-5'-carboxamide

生物活性

Description
MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM.
Targets
p53 MDM2
N/A0.88 nM

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.78 mL 88.89 mL 177.78mL
0.5 mM 3.56 mL 17.78 mL 35.56 mL
1 mM 1.78 mL 8.89 mL 17.78 mL
5 mM 0.36 mL 1.78 mL 3.56 mL

*The above data is based on the productmolecular weight 562.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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