MI-773
目录号: A15440
MDM2 抑制剂
MI-773是一种口服可用的MDM2拮抗剂,其Ki值为0.88 nM。
Discription | MI-773 is an orally available MDM2 antagonist with Ki of 0.88 nM. | ||
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Targets |
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目录号 | A15440 |
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分子式 | C29H34Cl2FN3O3 |
分子量 | 562.5 |
CAS号 | 1303607-60-4 |
SMILES | CC(C)(C)C[C@H]1[C@@]2([C@H]([C@@H](N1)C(=O)NC3CCC(CC3)O)C4=C(C(=CC=C4)Cl)F)C5=C(C=C(C=C5)Cl)NC2=O |
其他名称 | SAR405838,MI 773, MI773 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 93 mg/mL (165.33 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 29 mg/mL (51.55 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.78 mL | 88.89 mL | 177.78 mL |
0.5 mM | 3.56 mL | 17.78 mL | 35.56 mL |
1 mM | 1.78 mL | 8.89 mL | 17.78 mL |
5 mM | 0.36 mL | 1.78 mL | 3.56 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2