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Miltefosine

PI3K/Akt 抑制剂

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产品目录号: A14138

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Miltefosine 100mg A14138-100
¥ 650.00
Miltefosine 500mg A14138-500
¥ 1,900.00
Miltefosine 10mM * 1mL in DMSO A14138-10mM-D
¥ 640.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa

Miltefosine

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Chemical Information

目录号 A14138
Mechanism of action Inhibitor
分子量 407.6
化学分子式 C21H46NO4P
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 58066-85-6
Synonyms HePC
SMILES code CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+](C)(C)C
化学名称 1-?hexadecylphosphorylcholine

生物活性

Description
Miltefosine inhibits PI3K/Akt activity with ED50 of 17.2 μM and 8.1 μM in carcinoma cell lines A431 and HeLa
Targets
Akt PI3K PKC
N/A~7 μM

溶解性

Solubility (25°C) * In vitro DMSO 82 mg/mL (201.19 mM)
Water <1 mg/mL (<1 mM)
Ethanol 82 mg/mL (201.19 mM)
In vivo Saline 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.53 mL 122.67 mL 245.34mL
0.5 mM 4.91 mL 24.53 mL 49.07 mL
1 mM 2.45 mL 12.27 mL 24.53 mL
5 mM 0.49 mL 2.45 mL 4.91 mL

*The above data is based on the productmolecular weight 407.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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