(-)-MK 801 maleate (-)-Dizocilpine maleate
目录号: A13435
NMDA receptor 拮抗剂.
(-)-MK 801 maleate 作为一种强效、选择性且非竞争性的 NMDA 受体拮抗剂。它通过结合位于 NMDA 相关离子通道 内的一个位点来发挥作用。
| Discription | (-)-MK 801 maleate acts as a potent, selective, and non-competitive NMDA receptor antagonist. It acts by binding to a site located within the NMDA associated ion channel. | ||
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| 目录号 | A13435 |
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| 分子式 | C20H19NO4 |
| 分子量 | 337.37 |
| CAS号 | 121917-57-5 |
| SMILES | C[C@]12C3=CC=CC=C3C[C@H](N1)C4=CC=CC=C24.C(=C/C(=O)O)\C(=O)O |
| 其他名称 | MK801, MK-801 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 63 mg/mL (186.73 mM) | |
| Water | Insoluble | ||
| Ethanol | 7 mg/mL (20.74 mM) | ||
| In vivo | 2% DMSO+40% PEG 300+2% Tween 80+ddH2O | 7 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.64 mL | 148.21 mL | 296.41 mL |
| 0.5 mM | 5.93 mL | 29.64 mL | 59.28 mL |
| 1 mM | 2.96 mL | 14.82 mL | 29.64 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.93 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2