Mipasetamab is an IgG1?? monoclonal antibody specifically designed to target AXL, a member of the TAM family of receptor tyrosine kinases. This antibody plays a crucial role in the synthesis of ADCT-601 (Mipasetamab uzoptirine), an antibody-drug conjugate (ADC) that selectively binds to the AXL receptor. ADCT-601 demonstrates significant antitumor activity, leveraging the specificity of Mipasetamab to deliver cytotoxic agents directly to AXL-expressing tumor cells, thereby enhancing therapeutic efficacy while minimizing off-target effects. This product is pivotal for research focused on the development of targeted cancer therapies, particularly in studies investigating the role of AXL in cancer progression and resistance mechanisms.
Mipasetamab is an IgG1?? monoclonal antibody specifically designed to target AXL, a member of the TAM family of receptor tyrosine kinases. This antibody plays a crucial role in the synthesis of ADCT-601 (Mipasetamab uzoptirine), an antibody-drug conjugate (ADC) that selectively binds to the AXL receptor. ADCT-601 demonstrates significant antitumor activity, leveraging the specificity of Mipasetamab to deliver cytotoxic agents directly to AXL-expressing tumor cells, thereby enhancing therapeutic efficacy while minimizing off-target effects. This product is pivotal for research focused on the development of targeted cancer therapies, particularly in studies investigating the role of AXL in cancer progression and resistance mechanisms.
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