Mipletamig is a chimeric antibody comprising both human and humanized elements, specifically designed to target CD3E. Its structure includes a [(scFv -??-heavy) G1-h-CH2-CH3 (scFv-heavy -??)]2 format, integrating single-chain variable fragments (scFv) linked to the constant regions of human immunoglobulin G1 heavy chains (CH2-CH3). This antibody is engineered for high specificity and affinity toward CD3E, making it an invaluable tool in immunological research and therapeutic development.
Mipletamig is a chimeric antibody comprising both human and humanized elements, specifically designed to target CD3E. Its structure includes a [(scFv -??-heavy) G1-h-CH2-CH3 (scFv-heavy -??)]2 format, integrating single-chain variable fragments (scFv) linked to the constant regions of human immunoglobulin G1 heavy chains (CH2-CH3). This antibody is engineered for high specificity and affinity toward CD3E, making it an invaluable tool in immunological research and therapeutic development.
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