MJN110
目录号: A16081
MAGL 抑制剂
MJN110 是一种强效的选择性 MAGL 抑制剂,MAGL 是主要负责降解内源性大麻素 2-花生四烯酰甘油(2-AG)的酶,其对 FAAH 的选择性超过 10,000 倍,FAAH 是一种水解酶,负责降解内源性大麻素阿纳米特(AEA)。
Discription | MJN110 is a potent selective inhibitor of MAGL, the enzyme predominantly responsible for the degradation of the endocannabinoid 2-arachidonoylglycerol (2-AG) with >10,000 selectivity over FAAH, the hydrolase that degrades the endocannabinoid anandamide (AEA). |
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目录号 | A16081 |
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分子式 | C22H21Cl2N3O4 |
分子量 | 462.33 |
CAS号 | 1438416-21-7 |
SMILES | C1CC(=O)N(C1=O)OC(=O)N2CCN(CC2)C(C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)Cl |
其他名称 | MJN-110, MJN 110 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2