MK-0517 (Fosaprepitant)

目录号: A11756

neurokinin-1 receptor antagonist

MK-0517 (Fosaprepitant) Chemical Structure

CAS NO. 172673-20-0

Fosaprepitant (MK-0517, L-758,298) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,400.00
25 mg
¥ 2,500.00
50 mg
¥ 4,500.00
10mM * 1mL in DMSO
¥ 1,570.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Fosaprepitant (MK-0517, L-758,298) is a water-soluble phosphoryl prodrug for Aprepitant which is a NK1 antagonist.
In vitro DMSO 201 mg/mL (200.03 mM)
Water 135 mg/mL (134.35 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.28 mL 81.38 mL 162.76 mL
0.5 mM 3.26 mL 16.28 mL 32.55 mL
1 mM 1.63 mL 8.14 mL 16.28 mL
5 mM 0.33 mL 1.63 mL 3.26 mL

*The above data is based on the productmolecular weight 614.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11756
MECHANISM OF ACTION Antagonist
M. Wt 614.41
Formula C23H22F7N4O6P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 172673-20-0
Synonyms MK-0517, L-758,298
SMILES C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F

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