MK-0752

目录号: A11194

Gamma-secretase inhibitor

MK-0752 Chemical Structure

CAS NO. 471905-41-6

MK-0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated.

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,500.00
50 mg
¥ 5,500.00
100 mg
¥ 9,000.00
10mM * 1mL in DMSO
¥ 1,920.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

MK-0752 inhibits the Notch signaling pathway, which may result in induction of growth arrest and apoptosis in tumor cells in which the Notch signaling pathway is overactivated.
In vitro (25°C) DMSO 89 mg/mL (200.94 mM)
Water <1 mg/mL (<1 mM)
Ethanol 45 mg/mL (101.6 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.58 mL 112.89 mL 225.78 mL
0.5 mM 4.52 mL 22.58 mL 45.16 mL
1 mM 2.26 mL 11.29 mL 22.58 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11194
MECHANISM OF ACTION Inhibitor
M. Wt 442.9
Formula C21H21ClF2O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 471905-41-6
Synonyms MK0752
SMILES C1CC(CCC1CCC(=O)O)(C2=C(C=CC(=C2)F)F)S(=O)(=O)C3=CC=C(C=C3)Cl

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