Adavosertib (MK-1775)

Name: Adavosertib (MK-1775)
SKU: A10599
Price: 210 CNY
Rating: 5 (5 reviews)

目录号: A10599

WEE1 抑制剂

5 篇发表文献

MK-1775 是一种在体外和体内都具有强效和选择性的 Wee1激酶抑制剂。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥490.00	现货
50mg	¥560.00	现货
100mg	¥770.00	现货
200mg	¥1,155.00	现货
500mg	¥1,960.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Adavosertib (MK-1775)发表的5篇文献

Hayden L Bell, .et al. , Cancer Cell Int, 2023, Sep 15;23(1):202 PMID: 37715172

Chiao-Ping Chen, .et al. , Biomed Pharmacother, 2023, Oct:166:115389 PMID: 37659202

Ting-Yu Chang, .et al. , Biomed Pharmacother, 2021, Jun;138:111485 PMID: 33740521

2018, .et al. , FEBS Open Bio, 2018, Jun; 8(6): 1001-1012 PMID: 29928579

Rulina AV, .et al. , Cell Death Dis, 2016, Dec 1;7(12):e2505 PMID: 27906189

生物活性

Discription

MK-1775 is a potent and selective Wee1 kinase inhibitor in vitro and in vivo.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10599
分子式	C27H32N8O2
分子量	500.6
CAS号	955365-80-7
SMILES	CC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O
其他名称	AZD1775
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	71 mg/mL (141.82 mM)
	Water	Insoluble
	Ethanol	9 mg/mL (17.97 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.98 mL	99.88 mL	199.76 mL
0.5 mM	4 mL	19.98 mL	39.95 mL
1 mM	2 mL	9.99 mL	19.98 mL
5 mM	0.4 mL	2 mL	4 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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