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MK 3207 HCl

CGRP Receptor 拮抗剂

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产品目录号: A10598


产品名 目录号 价格 数量
MK 3207 hydrochloride 5mg A10598-5
¥ 1,200.00
MK 3207 hydrochloride 10mg A10598-10
¥ 2,300.00
MK 3207 hydrochloride 50mg A10598-50
¥ 6,800.00
MK 3207 hydrochloride 100mg A10598-100
¥ 12,000.00
MK 3207 HCl 10mM * 1mL in DMSO A10598-10mM-D
¥ 1,830.00



MK 3207 hydrochloride is a potent CGRP receptor antagonist with IC50 of 0.12 nM.

MK 3207 HCl




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 MK 3207 HCl 发表的文献 (1)
  • Marlene Dallmayer, .et al. Targeting the CALCB/RAMP1-axis inhibits growth of Ewing sarcoma, bioRxiv, 2018, 2018

Chemical Information

目录号 A10598
Mechanism of action Antagonist
分子量 594.1
化学分子式 C31H30ClF2N5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 957116-20-0
Synonyms MK3207, MK-3207
SMILES code C1CCC2(C1)C(=O)N([C@@H](CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(C[C@@]6(C5)C7=C(NC6=O)N=CC=C7)C=C4.Cl
化学名称 (8R)-8-(3,5-Difluorophenyl)-10-oxo-N-[(2R)-1,1',2',3-tetrahydro-2'-oxospiro[2H-indene-2,3'-[3H]pyrrolo[2,3-b]pyridin]-5-yl]-6,9-diazaspiro[4.5]decane-9-acetamide hydrochloride


MK 3207 hydrochloride is a potent CGRP receptor antagonist with IC50 of 0.12 nM.
0.12 nM


Solubility (25°C) * In vitro DMSO 119 mg/mL (200.31 mM)
Water 5 mg/mL (8.41 mM)
Ethanol 119 mg/mL (200.31 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.83 mL 84.16 mL 168.32mL
0.5 mM 3.37 mL 16.83 mL 33.66 mL
1 mM 1.68 mL 8.42 mL 16.83 mL
5 mM 0.34 mL 1.68 mL 3.37 mL

*The above data is based on the productmolecular weight 594.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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