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MK-571 sodium salt

CysLT1 receptor 拮抗剂

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产品目录号: A15983

库存状态:中国现货中国现货

产品名 目录号 价格 数量
MK-571 sodium salt 5mg A15983-5
¥ 450.00
MK-571 sodium salt 10mg A15983-10
¥ 800.00
MK-571 sodium salt 50mg A15983-50
¥ 3,200.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively.

MK-571 sodium salt

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Chemical Information

目录号 A15983
Mechanism of action Antagonist
分子量 537.06
化学分子式 C26H26ClN2NaO3S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 115103-85-0
Synonyms L-660,711, L660,711, L 660,711, L-660711
SMILES code O=C([O-])CCSC(C1=CC=CC(/C=C/C2=NC3=CC(Cl)=CC=C3C=C2)=C1)SCCC(N(C)C)=O.[Na+]
化学名称 sodium (E)-3-(((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)propanoate

生物活性

Description
MK-571 is a selective, orally active CysLT1 receptor antagonist. It blocks the binding of LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively.
Targets
CysLT1 MRP1 MRP4 cMOAT

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.62 mL 93.1 mL 186.2mL
0.5 mM 3.72 mL 18.62 mL 37.24 mL
1 mM 1.86 mL 9.31 mL 18.62 mL
5 mM 0.37 mL 1.86 mL 3.72 mL

*The above data is based on the productmolecular weight 537.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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