MK-6096 (Filorexant)

目录号: A13168

Orexin receptor 拮抗剂

MK-6096 (Filorexant)

MK-6096 (Filorexant) Chemical Structure

CAS NO. 1088991-73-4

MK-6096 (Filorexant)是目前正处于失眠临床开发中的口服生物利用型有效且选择性可逆的OX(1)R和OX(2)R拮抗剂。MK-6096表现出对人OX(1)R和OX(2)R的有效结合和拮抗作用(结合时<3 nM,FLIPR中为11 nM),对超过170个受体和 酶。

库存: 现货

规格 价格 数量
5 mg
¥ 750.00
25 mg
¥ 2,700.00
100 mg
¥ 6,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

MK-6096 (Filorexant)是目前正处于失眠临床开发中的口服生物利用型有效且选择性可逆的OX(1)R和OX(2)R拮抗剂。MK-6096表现出对人OX(1)R和OX(2)R的有效结合和拮抗作用(结合时<3 nM,FLIPR中为11 nM),对超过170个受体和 酶。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.78 mL 118.91 mL 237.82 mL
0.5 mM 4.76 mL 23.78 mL 47.56 mL
1 mM 2.38 mL 11.89 mL 23.78 mL
5 mM 0.48 mL 2.38 mL 4.76 mL

*The above data is based on the productmolecular weight 420.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A13168
作用机制 Antagonist (拮抗剂)
M. Wt 420.48
Formula C24H25FN4O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1088991-73-4
Synonyms MK6096, MK-6096, MK 6096
SMILES CC1=CC=C(C2=NC=CC=N2)C(C(N3C[C@@H](COC4=NC=C(F)C=C4)CC[C@@H]3C)=O)=C1

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