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c-Met 抑制剂

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产品目录号: A11489


产品名 目录号 价格 数量
MK-8033 5mg A11489-5
¥ 3,000.00
MK-8033 10mg A11489-10
¥ 5,500.00
MK-8033 25mg A11489-25
¥ 12,000.00



MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.





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Chemical Information

目录号 A11489
Mechanism of action Inhibitor
分子量 471.53
化学分子式 C25H21N5O3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1001917-37-8
Synonyms MK 8033, MK8033
SMILES code CN1C=C(C=N1)C2=CN=C3C=CC4=C(C=C(C=C4)CS(=O)(=O)NCC5=CC=CC=N5)C(=O)C3=C2
化学名称 1-[2-(1-methylpyrazol-4-yl)-11-oxobenzo[1,2]cyclohepta[2,4-b]pyridin-9-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide


MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.21 mL 106.04 mL 212.08mL
0.5 mM 4.24 mL 21.21 mL 42.42 mL
1 mM 2.12 mL 10.6 mL 21.21 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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