MK-8245 Trifluoroacetate

目录号: A15170

Liver-targeting SCD Inhibitor‎

MK-8245 Trifluoroacetate

MK-8245 Trifluoroacetate Chemical Structure

CAS NO. 1415559-41-9

MK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
50 mg
¥ 3,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

MK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.2 mL 86.02 mL 172.04 mL
0.5 mM 3.44 mL 17.2 mL 34.41 mL
1 mM 1.72 mL 8.6 mL 17.2 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15170
MECHANISM OF ACTION Inhibitor
M. Wt 581.27
Formula C19H17BrF4N6O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1415559-41-9
Synonyms MK 8245 Trifluoroacetate, MK8245 Trifluoroacetate
SMILES C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O.C(=O)(C(F)(F)F)O

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