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MK-8245 Trifluoroacetate

目录号: A15170

Liver-targeting SCD 抑制剂

MK-8245 三氟乙酸盐是一种针对肝脏的抑制剂,用于抑制硬脂酰辅酶A去饱和酶(SCD),对人类 SCD1 的 IC50 为 1 nM,对大鼠 SCD1 和小鼠 SCD1 均为 3 nM,具有抗糖尿病和抗血脂异常的功效。
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规格 价格 库存 数量
1mg
¥455.00
现货
5mg
¥665.00
现货
10mg
¥1,225.00
现货
50mg
¥2,695.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription MK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy.
产品信息
目录号 A15170
分子式 C19H17BrF4N6O6
分子量 581.27
CAS号 1415559-41-9
SMILES C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O.C(=O)(C(F)(F)F)O
其他名称 MK 8245 Trifluoroacetate, MK8245 Trifluoroacetate
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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