MK-8245 Trifluoroacetate

目录号: A15170

Liver-targeting SCD 抑制剂?

MK-8245 Trifluoroacetate

MK-8245 Trifluoroacetate Chemical Structure

CAS NO. 1415559-41-9

MK-8245 Trifluoroacetate是硬脂酰辅酶A去饱和酶(SCD)的肝靶向抑制剂,对人SCD1的IC50为1 nM,对大鼠SCD1和小鼠SCD1的IC50为3 nM,具有抗糖尿病和抗血脂异常的功效。

库存: 现货

规格 价格 数量
5 mg
¥ 1,000.00
10 mg
¥ 1,800.00
50 mg
¥ 3,900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

MK-8245 Trifluoroacetate是硬脂酰辅酶A去饱和酶(SCD)的肝靶向抑制剂,对人SCD1的IC50为1 nM,对大鼠SCD1和小鼠SCD1的IC50为3 nM,具有抗糖尿病和抗血脂异常的功效。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.2 mL 86.02 mL 172.04 mL
0.5 mM 3.44 mL 17.2 mL 34.41 mL
1 mM 1.72 mL 8.6 mL 17.2 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 581.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15170
作用机制 Inhibitor (抑制剂)
M. Wt 581.27
Formula C19H17BrF4N6O6
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1415559-41-9
Synonyms MK 8245 Trifluoroacetate, MK8245 Trifluoroacetate
SMILES C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O.C(=O)(C(F)(F)F)O

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