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MK-8245

目录号: A11403
SCD 抑制剂
MK-8245 是一种针对肝脏的硬脂酰辅酶A去饱和酶(SCD)抑制剂。MK-8245 对于治疗糖尿病血脂异常具有疗效。
Grouped product items
规格 价格 库存 数量
1mg
¥175.00
现货
2mg
¥280.00
现货
5mg
¥630.00
现货
10mg
¥1,050.00
现货
25mg
¥1,960.00
现货
50mg
¥3,360.00
现货
100mg
¥4,690.00
现货
10mM * 1mL in DMSO
¥525.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用MK-8245发表的1篇文献
  • Miyayama Y, .et al. , Microbiol Immunol, 2019, Dec 19 PMID: 31854467
  • 生物活性
    Discription MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A11403
    分子式 C17H16BrFN6O4
    分子量 467.3
    CAS号 1030612-90-8
    SMILES C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O
    其他名称 MK8245
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 89 mg/mL (190.47 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% CMC+0.5% Tween-80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.4 mL 107 mL 214 mL
    0.5 mM 4.28 mL 21.4 mL 42.8 mL
    1 mM 2.14 mL 10.7 mL 21.4 mL
    5 mM 0.43 mL 2.14 mL 4.28 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

    • Calculator Reset
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