MK-8245

目录号: A11403

SCD inhibitor

MK-8245

MK-8245 Chemical Structure

CAS NO. 1030612-90-8, 1030612-87-3

MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.

库存: 现货

规格 价格 数量
5 mg
¥ 1,600.00
10 mg
¥ 2,800.00
50 mg
¥ 8,200.00
100 mg
¥ 14,000.00
10mM * 1mL in DMSO
¥ 2,090.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
Targets
SCD1 (human) SCD1 (rat) SCD1 (mouse)
1 nM3 nM3 nM
In vitro (25°C) DMSO 93 mg/mL (199.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% CMC/0.5% Tween-80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.4 mL 107 mL 214 mL
0.5 mM 4.28 mL 21.4 mL 42.8 mL
1 mM 2.14 mL 10.7 mL 21.4 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11403
MECHANISM OF ACTION Inhibitor
M. Wt 467.3
Formula C17H16BrFN6O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1030612-90-8, 1030612-87-3
Synonyms MK8245
SMILES C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O

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