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SCD 抑制剂

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产品目录号: A11403


产品名 目录号 价格 数量
MK-8245 5mg A11403-5
¥ 1,600.00
MK-8245 10mg A11403-10
¥ 2,800.00
MK-8245 50mg A11403-50
¥ 8,200.00
MK-8245 100mg A11403-100
¥ 14,000.00
MK-8245 10mM * 1mL in DMSO A11403-10mM-D
¥ 2,090.00



MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A11403
Mechanism of action Inhibitor
分子量 467.3
化学分子式 C17H16BrFN6O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1030612-90-8, 1030612-87-3
Synonyms MK8245
SMILES code C1CN(CCC1OC2=C(C=CC(=C2)F)Br)C3=NOC(=C3)C4=NN(N=N4)CC(=O)O
化学名称 4-(2-Bromo-5-fluorophenoxy)-1-[5-(2H-tetrazol-5-yl)-3-isoxazolyl]piperidine


MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia.
SCD1 (human) SCD1 (rat) SCD1 (mouse)
1 nM3 nM3 nM


Solubility (25°C) * In vitro DMSO 93 mg/mL (199.03 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 1% CMC/0.5% Tween-80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.4 mL 107 mL 214mL
0.5 mM 4.28 mL 21.4 mL 42.8 mL
1 mM 2.14 mL 10.7 mL 21.4 mL
5 mM 0.43 mL 2.14 mL 4.28 mL

*The above data is based on the productmolecular weight 467.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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