MK-8617

Name: MK-8617
SKU: A12618
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A12618

pan HIF PHD1-3 抑制剂

MK-8617 是一种口服活性的广谱抑制剂，针对低氧诱导因子脯氨酸羟化酶 1-3（HIF PHD1-3），对 PHD2 的 IC50 为 1 nM。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥385.00	现货
25mg	¥840.00	现货
50mg	¥1,645.00	现货
100mg	¥2,765.00	现货
200mg	¥4,060.00	现货
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Data Sheet

SDS

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生物活性

Discription	MK-8617 is an orally active pan-inhibitor of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) with an IC50 of 1 nM for PHD2.

产品信息

目录号	A12618
分子式	C24H21N5O4
分子量	443.45
CAS号	1187990-87-9
SMILES	O=C(C1=CN=C(C2=NN=CC=C2)N=C1O)NC(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4
其他名称	MK 8617, MK8617
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 17 mg/mL (38.34 mM)
	Water	Insoluble
	Ethanol	1 mg/mL (2.25 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.55 mL	112.75 mL	225.5 mL
0.5 mM	4.51 mL	22.55 mL	45.1 mL
1 mM	2.26 mL	11.28 mL	22.55 mL
5 mM	0.45 mL	2.26 mL	4.51 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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