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MKT 077

促销

HSP70 抑制剂

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产品目录号: A12388

库存状态:中国现货中国现货

产品名 目录号 价格 数量
MKT 077 5mg A12388-5
¥ 600.00
MKT 077 10mg A12388-10
¥ 1,200.00
MKT 077 25mg A12388-25
¥ 2,000.00
MKT 077 100mg A12388-100
¥ 3,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.

MKT 077

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Chemical Information

目录号 A12388
Mechanism of action Inhibitor
分子量 432
化学分子式 C21H22ClN3OS2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 147366-41-4
Synonyms MKT077, MKT-077
SMILES code CCN1/C(=C/C2=CC=CC=[N+]2CC)/S/C(=C/3\N(C4=CC=CC=C4S3)C)/C1=O.[Cl-]
化学名称 1-Ethyl-2-[[3-ethyl-5-(3-methyl-2(3?H)-benzothiazolylidene)-4-oxo-2-thiazolidinylidene?]methyl]-pyridinium chloride

生物活性

Description
Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.15 mL 115.74 mL 231.48mL
0.5 mM 4.63 mL 23.15 mL 46.3 mL
1 mM 2.31 mL 11.57 mL 23.15 mL
5 mM 0.46 mL 2.31 mL 4.63 mL

*The above data is based on the productmolecular weight 432. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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