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ML 193 is a selective GPR55 antagonist (IC50 = 221 nM). Exhibits >27-, >145- and >145-fold selectivity for GPR55 over CB1, GPR35 and CB2, respectively. Inhibits ERK signaling in vitro.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.95 mL | 94.77 mL | 189.54 mL |
| 0.5 mM | 3.79 mL | 18.95 mL | 37.91 mL |
| 1 mM | 1.9 mL | 9.48 mL | 18.95 mL |
| 5 mM | 0.38 mL | 1.9 mL | 3.79 mL |
*The above data is based on the productmolecular weight 527.599. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22553 |
|---|---|
| M. Wt | 527.599 |
| Formula | C28H25N5O4S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 713121-80-3 |
| Synonyms | ML-193, ML 193, ML193, CID 1261822, CID-1261822, CID1261822. |
| SMILES | O=C(C1=CC(C2=NC=CC=C2)=NC3=C(C)C=C(C)C=C13)NC4=CC=C(S(=O)(NC5=C(C)C(C)=NO5)=O)C=C4 |
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