ML-323
目录号: A14030
USP1-UAF1 抑制剂
ML323 是一种选择性且高效的 USP1-UAF1 抑制剂，将去泛素化与 DNA 损伤反应联系起来。
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生物活性
| Discription | ML323 is a selective and highly potent USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. | ||
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| Targets |
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产品信息
| 目录号 | A14030 |
|---|---|
| 分子式 | C23H24N6 |
| 分子量 | 384.20624 |
| CAS号 | 1572414-83-5 |
| SMILES | CC1=CN=C(N=C1NCC2=CC=C(C=C2)N3C=CN=N3)C4=CC=CC=C4C(C)C |
| 其他名称 | ML323, ML 323 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 65 mg/mL (169.05 mM) | |
| Water | Insoluble | ||
| Ethanol | 33 mg/mL (85.83 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.03 mL | 130.14 mL | 260.28 mL |
| 0.5 mM | 5.21 mL | 26.03 mL | 52.06 mL |
| 1 mM | 2.6 mL | 13.01 mL | 26.03 mL |
| 5 mM | 0.52 mL | 2.6 mL | 5.21 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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