ML 786 dihydrochloride

目录号: A11211

Raf inhibitor

ML 786 dihydrochloride Chemical Structure

CAS NO. 1237536-18-3

ML 786 dihydrochloride is a potent Raf kinase inhibitor (IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively).

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,500.00
50 mg
¥ 8,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

ML 786 dihydrochloride is a potent Raf kinase inhibitor (IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.35 mL 81.77 mL 163.54 mL
0.5 mM 3.27 mL 16.35 mL 32.71 mL
1 mM 1.64 mL 8.18 mL 16.35 mL
5 mM 0.33 mL 1.64 mL 3.27 mL

*The above data is based on the productmolecular weight 611.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11211
MECHANISM OF ACTION Inhibitor
M. Wt 611.48
Formula C29H29F3N4O3.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1237536-18-3
Synonyms ML786 dihydrochloride
SMILES CC(C)(C1=CC(=CC(=C1)C(=O)NC2CCC3=C(C2)C=C(C=C3)OC4=C5CCC(=O)NC5=NC=C4)C(F)(F)F)N.Cl.Cl

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