ML-792
目录号: A16832
SAE 抑制剂
ML-792 是一种强效且选择性的 SAE 抑制剂，在细胞实验中具有纳摩尔级的效力。ML-792 选择性地阻断 SAE 酶活性 和总 SUMOylation，从而减少癌细胞的增殖。
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生物活性
| Discription | ML-792 is a potent and selective SAE inhibitor with nanomolar potency in cellular assays. ML-792 selectively blocks SAE enzyme activity and total SUMOylation, thus decreasing cancer cell proliferation. | |||||
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| Cell Research |
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产品信息
| 目录号 | A16832 |
|---|---|
| 分子式 | C21H23BrN6O5S |
| 分子量 | 551.42 |
| CAS号 | 1644342-14-2 |
| SMILES | O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=NN(CC4=CC=CC(Br)=C4)C=C3)=O)C1)(N)=O |
| 其他名称 | ML 792, ML792 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 90 mg/mL (163.22 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.13 mL | 90.67 mL | 181.35 mL |
| 0.5 mM | 3.63 mL | 18.13 mL | 36.27 mL |
| 1 mM | 1.81 mL | 9.07 mL | 18.13 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.63 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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