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ML162 is a covalent glutathione peroxidase 4 (GPX4) inhibitor. ML162 has a selective lethal effect on mutant RAS oncogene-expressing cell lines.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.95 mL | 104.73 mL | 209.47 mL |
| 0.5 mM | 4.19 mL | 20.95 mL | 41.89 mL |
| 1 mM | 2.09 mL | 10.47 mL | 20.95 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22418 |
|---|---|
| M. Wt | 477.4 |
| Formula | C23H22Cl2N2O3S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 1035072-16-2 |
| Synonyms | ML-162,ML 162 |
| SMILES | O=C(CCl)N(C(C1=CC=CS1)C(NCCC2=CC=CC=C2)=O)C3=CC=C(OC)C(Cl)=C3 |
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