ML355

Name: ML355
SKU: A18349
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A18349

12-Lipoxygenase (12-LOX) 抑制剂

ML355 是一种强效且选择性的 12-脂氧合酶（12-LOX）抑制剂，其 IC50 为 0.34 μM，对相关的脂氧合酶和环氧合酶显示出极佳的选择性，并具有良好的 ADME 特性。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
5mg	¥630.00	现货
10mg	¥1,085.00	现货
25mg	¥2,135.00	现货
50mg	¥3,535.00	现货
100mg	¥5,460.00	现货
200mg	¥7,455.00	现货
*10mM 1mL in DMSO**	¥665.00	现货
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Data Sheet

SDS

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生物活性

Discription

ML355 is a potent and selective inhibitor of 12-Lipoxygenase (12-LOX) with an IC50 of 0.34 μM, shows excellent selectivity over related lipoxygenases and cyclooxygenases, and possesses favorable ADME properties.

Targets

Target	Value

产品信息

目录号	A18349
分子式	C21H19N3O4S2
分子量	441.52
CAS号	1532593-30-8
SMILES	O=S(C1=CC=C(NCC2=CC=CC(OC)=C2O)C=C1)(NC3=NC4=CC=CC=C4S3)=O
其他名称	ML 355, ML-355
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	86 mg/mL (194.78 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.65 mL	113.25 mL	226.49 mL
0.5 mM	4.53 mL	22.65 mL	45.3 mL
1 mM	2.26 mL	11.32 mL	22.65 mL
5 mM	0.45 mL	2.26 mL	4.53 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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