ML418
目录号: A18426
Kir7.1 potassium channels blocker
ML418 是一种选择性的、亚微摩尔级的 Kir7.1 钾通道孔阻断剂。内向整流钾(Kir)通道 Kir7.1 (KCNJ13) 是大脑中黑色素皮质素信号传导、眼部电解质平衡以及妊娠期间子宫肌肉收缩的关键调节器。
Discription | ML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. |
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目录号 | A18426 |
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分子式 | C19H24ClN3O3 |
分子量 | 377.87 |
CAS号 | 1928763-08-9 |
SMILES | O=C(OC(C)C)NC1CCN(CC2=CC(Cl)=C3C=CC=NC3=C2O)CC1 |
其他名称 | ML418; ML-418; ML 418 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2