MLN1117 (Serabelisib)
目录号: A15529
p110α 抑制剂
MLN1117,也被称为INK1117和TAK-117,是一种口服生物可利用的一类磷脂酰肌醇3激酶(PI3K)α亚型抑制剂,具有潜在的抗肿瘤活性。
Discription | MLN1117, also known as INK1117 and TAK-117, is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha isoform with potential antineoplastic activity. | ||
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目录号 | A15529 |
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分子式 | C19H17N5O3 |
分子量 | 363.13 |
CAS号 | 1268454-23-4 |
SMILES | O=C(C1=CN=C2C=CC(C3=CC=C(OC(N)=N4)C4=C3)=CN21)N5CCOCC5 |
其他名称 | INK1117, INK-1117, INK 1117, MLN 1117, MLN-1117, TAK-117, TAK 117, TAK117 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 15 mg/mL (41.28 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 27.54 mL | 137.69 mL | 275.38 mL |
0.5 mM | 5.51 mL | 27.54 mL | 55.08 mL |
1 mM | 2.75 mL | 13.77 mL | 27.54 mL |
5 mM | 0.55 mL | 2.75 mL | 5.51 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2