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MLN2480 (BIIB-024)

pan-Raf 抑制剂

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产品目录号: A11240

库存状态:中国现货中国现货

产品名 目录号 价格 数量
MLN2480 (BIIB-024) 5mg A11240-5
¥ 1,500.00
MLN2480 (BIIB-024) 10mg A11240-10
¥ 2,500.00
MLN2480 (BIIB-024) 25mg A11240-25
¥ 4,800.00
MLN2480 (BIIB-024) 50mg A11240-50
¥ 8,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

MLN 2480 is an oral, selective pan-Raf kinase inhibitor in chinical trials.

MLN2480 (BIIB-024)

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Chemical Information

目录号 A11240
Mechanism of action Inhibitor
分子量 506.29
化学分子式 C17H12Cl2F3N7O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1096708-71-2
Synonyms MLN-2480,BIIB 024, BIIB-024
SMILES code C[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
化学名称 6-Amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]-2-thiazolyl]ethyl]-4-pyrimidinecarboxamide

生物活性

Description
MLN 2480 is an oral, selective pan-Raf kinase inhibitor in chinical trials.
Targets
Raf

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.75 mL 98.76 mL 197.52mL
0.5 mM 3.95 mL 19.75 mL 39.5 mL
1 mM 1.98 mL 9.88 mL 19.75 mL
5 mM 0.4 mL 1.98 mL 3.95 mL

*The above data is based on the productmolecular weight 506.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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