MLN9708

目录号: A10602

Proteasome 抑制剂

MLN9708

MLN9708 Chemical Structure

CAS NO. 1201902-80-8

MLN9708是一种蛋白酶体抑制剂,可抑制蛋白酶体的活性,从而阻断通常由蛋白酶体进行的靶向蛋白水解。

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 800.00
50 mg
¥ 1,500.00
100 mg
¥ 2,500.00
10mM * 1mL in DMSO
¥ 600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

MLN9708是一种蛋白酶体抑制剂,可抑制蛋白酶体的活性,从而阻断通常由蛋白酶体进行的靶向蛋白水解。
靶点信息
20S proteasome (Cell-free assay) 20S proteasome (Cell-free assay)
0.93 nM(Ki)3.4 nM
In vitro (25°C) DMSO 100 mg/mL (193.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.34 mL 96.69 mL 193.39 mL
0.5 mM 3.87 mL 19.34 mL 38.68 mL
1 mM 1.93 mL 9.67 mL 19.34 mL
5 mM 0.39 mL 1.93 mL 3.87 mL

*The above data is based on the productmolecular weight 517.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10602
作用机制 Inhibitor (抑制剂)
M. Wt 517.1
Formula C20H23BCl2N2O9
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1201902-80-8
Synonyms MLN-9708
SMILES B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)[C@H](CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl

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