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Proteasome 抑制剂

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产品目录号: A10602


产品名 目录号 价格 数量
MLN9708 5mg A10602-5
¥ 600.00
MLN9708 10mg A10602-10
¥ 800.00
MLN9708 50mg A10602-50
¥ 1,500.00
MLN9708 100mg A10602-100
¥ 2,500.00
MLN9708 10mM * 1mL in DMSO A10602-10mM-D
¥ 600.00



MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.





顾客使用 Adooq 产品发表的高质量科研文献

Chemical Information

目录号 A10602
Mechanism of action Inhibitor
分子量 517.1
化学分子式 C20H23BCl2N2O9
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1201902-80-8
Synonyms MLN-9708
SMILES code B1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)[C@H](CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
化学名称 4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid


MLN9708 is a proteasome inhibitor, which inhibits the activity of the proteasome, blocking the targeted proteolysis normally performed by the proteasome.
20S proteasome (Cell-free assay) 20S proteasome (Cell-free assay)
0.93 nM(Ki)3.4 nM


Solubility (25°C) * In vitro DMSO 100 mg/mL (193.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% hydroxyethyl cellulose 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.34 mL 96.69 mL 193.39mL
0.5 mM 3.87 mL 19.34 mL 38.68 mL
1 mM 1.93 mL 9.67 mL 19.34 mL
5 mM 0.39 mL 1.93 mL 3.87 mL

*The above data is based on the productmolecular weight 517.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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