MLT-748
目录号: A18954
MALT1 抑制剂
MLT-748 是一种强效、选择性的 MALT1 选择性抑制剂,它通过与 MALT1 的 变构 Trp580 口袋结合,具有 5 nM 的 IC50。
Discription | MLT-748 is a potent, selective and allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM. |
---|
目录号 | A18954 |
---|---|
分子式 | C19H19Cl2N9O3 |
分子量 | 492.32 |
CAS号 | 1832578-30-9 |
SMILES | O=C(NC1=CC(Cl)=C(N2N=CC=N2)N=C1)NC3=C([C@@H](OC)[C@H](OC)C)N4C(N=C3)=CC(Cl)=N4 |
其他名称 | MLT748, MLT 748 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 88 mg/mL (178.74 mM) | |
Water | Insoluble | ||
Ethanol | 9 mg/mL (18.28 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.31 mL | 101.56 mL | 203.12 mL |
0.5 mM | 4.06 mL | 20.31 mL | 40.62 mL |
1 mM | 2.03 mL | 10.16 mL | 20.31 mL |
5 mM | 0.41 mL | 2.03 mL | 4.06 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2