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MMV008138

目录号: A19169
targeting antimalarial agent
MMV008138 是一种选择性针对 IspD(酶2-C-甲基-D-赤藓糖醇4-磷酸胞苷转移酶)的抗疟疾药物,对 PfIspD(疟原虫 IspD)的 IC50 为 44 nM。MMV008138 抑制疟原虫 Dd2 株的生长,其 IC50 为 250 nM。
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规格 价格 库存 数量
5mg
¥2,485.00
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10mg
¥4,305.00
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25mg
¥9,975.00
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50mg
¥12,845.00
现货
100mg
¥17,465.00
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10mM * 1mL in DMSO
¥2,975.00
现货
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生物活性
Discription MMV008138 is a species-selective IspD (enzyme 2-C-methyl-d-erythritol 4-phosphate cytidylyltransferase)-targeting antimalarial agent, with an IC50 of 44 nM for PfIspD (P. falciparum IspD). MMV008138 inhibits the growth of P. falciparum Dd2 strain with an IC50 of 250 nM.
产品信息
目录号 A19169
分子式 C18H14Cl2N2O2
分子量 361.22
CAS号 1679333-73-3
SMILES O=C([C@@H]1CC2=C([C@@H](C3=CC=C(Cl)C=C3Cl)N1)NC4=C2C=CC=C4)O
其他名称 MMV 008138, MMV-008138
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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Please check COA/MSDS for correct molecular weight.

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This equation is commonly abbreviated as: C1V1 = C2V2

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