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Mobocertinib (TAK-788) is a potent and orally active inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, with selectivity over WT EGFR. Antitumor activity.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.07 mL | 85.37 mL | 170.74 mL |
0.5 mM | 3.41 mL | 17.07 mL | 34.15 mL |
1 mM | 1.71 mL | 8.54 mL | 17.07 mL |
5 mM | 0.34 mL | 1.71 mL | 3.41 mL |
*The above data is based on the productmolecular weight 585.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A22334 |
---|---|
M. Wt | 585.7 |
Formula | C32H39N7O4 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 2 years |
CAS No. | 1847461-43-1 |
Synonyms | TAK-788; AP32788 |
SMILES | O=C(C1=CN=C(NC2=CC(NC(C=C)=O)=C(N(CCN(C)C)C)C=C2OC)N=C1C3=CN(C)C4=C3C=CC=C4)OC(C)C |
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