Modotuximab (DS 1024) is a chimeric monoclonal antibody of the IgG1?? isotype, designed to specifically target the human Epidermal Growth Factor Receptor (EGFR). This antibody recognizes non-overlapping epitopes located on domain III of the EGFR protein, a region preserved in the EGFR variant III (EGFRvIII). Modotuximab demonstrates potent antitumor activity in vivo, making it a valuable tool for research in cancer biology and therapeutic development.
Modotuximab (DS 1024) is a chimeric monoclonal antibody of the IgG1?? isotype, designed to specifically target the human Epidermal Growth Factor Receptor (EGFR). This antibody recognizes non-overlapping epitopes located on domain III of the EGFR protein, a region preserved in the EGFR variant III (EGFRvIII). Modotuximab demonstrates potent antitumor activity in vivo, making it a valuable tool for research in cancer biology and therapeutic development.
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